Background & Aims: Enteroendocrine cells (EECs) are specialized epithelial cells that produce molecules vital for intestinal homeostasis, but because of their limited numbers, in-depth functional studies have remained challenging.Human intestinal enteroids (HIEs) that are derived from intestinal crypt stem cells are biologically relevant Saddle pad
The influence of microbial colonization on inflammatory versus pro-healing trajectories in combat extremity wounds
Abstract A combination of improved body armor, medical transportation, CLOVE and treatment has led to the increased survival of warfighters from combat extremity injuries predominantly caused by blasts in modern conflicts.Despite advances, a high rate of complications such as wound infections, wound failure, amputations, and a decreased quality of
Long-Term High-Density Extracellular Recordings Enable Studies of Muscle Cell Physiology
Skeletal (voluntary) muscle is the most abundant tissue in the body, thus making it an important biomedical research subject.Studies of neuromuscular transmission, including disorders of ion channels or receptors in autoimmune or genetic neuromuscular disorders, require high-spatial-resolution measurement techniques and an ability to acquire repeat
An augmented sweep clustering method for inventory-routing problem with simultaneous pickup and delivery considering lateral transshipment between repair centers
In this paper, an inventory-routing problem for a network of appliance repair service is discussed including several repair depots and customers.The customer in this network makes a demand to have his/her faulty appliance repaired.Then, the repairman is assigned to the demand based on the skill needed for repairing of appliance differing for each o